Estudos espectroscópicos da Interação do Cloridrato da N´-[(E)-2-Piridilmetileno] Isonicotinohidrazona com Albumina de soro bovino.

Espectroscopic studies of the interaction between bovine serum Albumin and the chlorhydride of Pyrimidil-Methyl-Isonicotinohidrazone.

Results shown

The poster shows the results of our espectroscopic studies of the interaction between bovine serum Albumin and the chlorhydride of Pyrimidil-Methyl-Isonicotinohidrazone. We used UV-Vis to characterize the stoichiometry of the complex as 1:1. T1 NMR experiments revealed the hydrogens that interact with the Albumin. It is clearly visible that chlorhydride interacts nicely, without beeing influenced by the fact that it is a salt.

Literature cited

The following literature references are used for this poster:

  1. http://www.fiocruz.br/ccs/glossario/tuberculose.htm
  2. Xiao, J. B. et al., J. Photochem. Photobiol. A 2007, 191, 222.
  3. Carvalho, E. M. et al., J. Mag. Reson. 2003, 164, 197-204.
  4. Neves, Ji, I.; Lourenço, M. C. S.; Henriques, M. G. M. O.;Ferreira, B. V.; Peralta, M. A.; Oliveira, P. S. M.; Wardell, S. M. S. V.; de Souza, M. V. N.; Lett. Drug. Discov. 2006, 3, 424.
The Poster

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